鈥嬪崡嫻鋒墍鐮旂┒鎻ず涓崕椴庡閲嶉噾灞為晧鐨勮В姣掓満鍒?/h3>
榪戞棩錛屼腑鍥芥按浜х瀛︾爺絀墮櫌鍗楁搗姘翠駭鐮旂┒鎵�涓崕椴庝繚鎶ょ爺絀跺洟闃熷湪鍒╃敤杞綍緇勪笌浠ｈ阿緇勬妧鏈垎鏋愰晧鏆撮湶涓嬩腑鍗庨矌騫奸矌鐨勮В姣掓満鍒剁爺絀舵柟闈㈠彇寰楁柊榪涘睍錛岀爺絀舵垚鏋滀互鈥淎 novel cadmium detoxification pathway in Tri-spine horseshoe crab (Tachypleus tridentatus)錛欰 430-million-years-ago organism鈥濅負棰樺彂琛ㄤ簬Ecotoxicology and Environmental Safety (IF 7.129)錛堝簲绱枃涓虹涓�浣滆�咃紝棰夋檽鍕囧崥澹負閫氳浣滆�咃級錛屼負涓崕椴庢爾鎭湴鐜璇勪及鍜屽孌栨斁嫻佸湴鐐歸�夋嫨鏂歸潰鎻愪緵浜嗙悊璁轟緷鎹紝榪樹負鍚庣畫涓崕椴庨噸閲戝睘鑳佽揩鐮旂┒鎻愬嚭浜嗘柊鎬濊礬銆?nbsp;
椴庢槸鏈�鍙よ�佺殑嫻鋒磱鏃犺剨妞庡姩鐗╀箣涓�錛屽湪榪囧幓鐨?.3浜垮勾閲岋紝鍏跺瑙傚嚑涔庢病鏈夊彉鍖栥�備腑鍗庨矌鏄疆闂村甫搴曟爾鐢熺墿錛屽湪娼棿甯︾敓鎬佺郴緇熶腑鍙戞尌閲嶈浣滅敤錛屽洜鍏剁壒孌婄敓澧冮渶姹傝瑙嗕負鐩戞祴娌挎搗鐜鍋ュ悍鐘跺喌鐨勬寚紺虹墿縐嶅拰鍓嶅摠鐗╃銆傞晧鏄搗宀稿甫鍜屾渤鍙ｇ幆澧冧腑鏅亶瀛樺湪鐨勬瘨鎬ц緝寮虹殑閲嶉噾灞炰箣涓�錛屽箍娉涘瓨鍦ㄤ簬娼棿甯︽矇縐墿涓�傛矇縐墿涓綔鍦ㄩ噴鏀劇殑闀夌瀛愭渶緇堥殢鍦拌〃寰勬祦榪涘叆娌挎搗姘村煙錛屼笉鍙伩鍏嶅湴鎹熷涓崕椴庛�備粠姣掔悊瀛﹁搴︽潵鐪嬶紝涓庝紶緇熸柟娉曠浉姣旓紝緇勫鍙互鏇寸洿鎺ャ�佸噯紜湴鍙嶆槧涓嶈壇鍚庢灉鐩稿叧鐨勫垎瀛愬姩鎬併�傛埅鑷崇洰鍓嶏紝閲嶉噾灞炴瘨鎬х爺絀朵富瑕侀泦涓簬椴庡嵉銆傚浜庢垚椴庯紝杈冨鐮旂┒嫻嬪畾鍏惰韓浣撳悇緇勭粐涓噸閲戝睘鍚噺銆傚皻鏃犲叧浜庢暣鍚堣漿褰曠粍瀛﹀拰浠ｈ阿緇勫璇勪及闀夊涓崕椴庡辜椴庢瘨鎬т綔鐢ㄧ殑鐩稿叧鐮旂┒鎶ラ亾銆?/p>
鍗楁搗鎵�椴庝繚鎶ゅ洟闃熺患鍚堟姉姘у寲鎸囨爣鍙婅漿褰曠粍瀛﹀拰浠ｈ阿緇勫鍒嗘瀽浜嗕腑鍗庨矌騫奸矌鐨勯晧瑙ｆ瘨鏈哄埗錛氾紙1錛夐嬈＄瓫閫夊嚭涓崕椴庡辜椴庨噸閲戝睘鑳佽揩涓嬬殑鏈�閫傚唴鍙傚熀鍥犱負Actin-related protein 5 (ARP5)銆傝綆梀n/n+1寰楀埌ARP5/SDHA銆丼DHA/18S rRNA鍜孉RP5/18S rRNA緇勫悎鍧囬�傜敤浜巕RT-PCR鍒嗘瀽涓崕椴庡辜椴庨噸閲戝睘鑳佽揩鍙嶅簲銆?nbsp;
浣跨敤geNorm杞歡璁＄畻娼滃湪鍐呭弬鍩哄洜騫沖潎琛ㄨ揪紼沖畾鍊糓 (A)鍜屾垚瀵瑰彉鍖栧�糣 (B)
娉細CD涓洪晧鑳佽揩錛汬G涓烘睘鑳佽揩
錛?錛夋姉姘у寲鎸囨爣SOD銆丆AT銆丮DA銆丮T鐨勬祴瀹氱粨鏋滄樉紺猴細闀夎儊榪細閫犳垚騫奸矌姘у寲搴旀縺鍙嶅簲錛屼笖闅忛晧嫻撳害鍗囬珮錛屽騫奸矌鍗卞涔熼殢涔嬪姞鍓с�?/p>
涓嶅悓嫻撳害闀夊SOD (a)鍜孋AT (b)鐨勬椿鎬с�丮DA鍚噺 (c)鍜孧T嫻撳害 (d)鐨勫獎鍝?/span>
錛?錛夎漿褰曠粍瀛﹀拰浠ｈ阿緇勫鍒嗘瀽鏄劇ず錛岄珮?gòu)箵搴﹂晧鑳仒q鑷翠腑鍗庨矌騫奸矌鐢樻補紓瘋剛浠ｈ阿绱婁貢浠ョ紦瑙ｉ晧鐨勬瘨鎬т綔鐢ㄣ�?/p>
緇煎悎杞綍緇勫拰浠ｈ阿緇勭殑鐩鎬簰緗戠粶錛堜嬌鐢∕etscape錛夈�傚熀鍥犱互鍦嗗湀琛ㄧず錛岃緭鍏ョ殑浠ｈ阿鐗╀互綰㈣壊鍏竟褰㈣〃紺恒�傜矇綰㈣壊鍏竟褰唬琛ㄤ竴鑸唬璋㈢墿錛屾綰㈣壊鍏竟褰唬琛ㄩ晧鑳佽揩涓嬪辜椴庡樊寮備唬璋㈢墿銆?/span>
錛?錛夊湪宸紓鍩哄洜涓紝緇嗚優(yōu)楠ㄦ灦鐩稿叧鍩哄洜 錛?em>tubulin銆乤ctin鍜?em>myosin heavy chain絳夛級鍦ㄩ晧鑳佽揩鍚庤榪囧害琛ㄨ揪錛岃�岃繖浜涘熀鍥犲浣曞弬涓庣粏鑳?yōu)楠ㄦ瀴檱嶅杩橀渶榪涗竴姝ョ爺絀躲�?/p>
鍏ㄦ枃閾炬帴錛?a >https://www.sciencedirect.com/science/article/pii/S0147651323000891
寰俊鎵竴鎵?br>鍒嗕韓鍒版湅鍙嬪湀
榪戞棩錛屼腑鍥芥按浜х瀛︾爺絀墮櫌鍗楁搗姘翠駭鐮旂┒鎵�涓崕椴庝繚鎶ょ爺絀跺洟闃熷湪鍒╃敤杞綍緇勪笌浠ｈ阿緇勬妧鏈垎鏋愰晧鏆撮湶涓嬩腑鍗庨矌騫奸矌鐨勮В姣掓満鍒剁爺絀舵柟闈㈠彇寰楁柊榪涘睍錛岀爺絀舵垚鏋滀互鈥淎 novel cadmium detoxification pathway in Tri-spine horseshoe crab (Tachypleus tridentatus)錛欰 430-million-years-ago organism鈥濅負棰樺彂琛ㄤ簬Ecotoxicology and Environmental Safety (IF 7.129)錛堝簲绱枃涓虹涓�浣滆�咃紝棰夋檽鍕囧崥澹負閫氳浣滆�咃級錛屼負涓崕椴庢爾鎭湴鐜璇勪及鍜屽孌栨斁嫻佸湴鐐歸�夋嫨鏂歸潰鎻愪緵浜嗙悊璁轟緷鎹紝榪樹負鍚庣畫涓崕椴庨噸閲戝睘鑳佽揩鐮旂┒鎻愬嚭浜嗘柊鎬濊礬銆?nbsp;
椴庢槸鏈�鍙よ�佺殑嫻鋒磱鏃犺剨妞庡姩鐗╀箣涓�錛屽湪榪囧幓鐨?.3浜垮勾閲岋紝鍏跺瑙傚嚑涔庢病鏈夊彉鍖栥�備腑鍗庨矌鏄疆闂村甫搴曟爾鐢熺墿錛屽湪娼棿甯︾敓鎬佺郴緇熶腑鍙戞尌閲嶈浣滅敤錛屽洜鍏剁壒孌婄敓澧冮渶姹傝瑙嗕負鐩戞祴娌挎搗鐜鍋ュ悍鐘跺喌鐨勬寚紺虹墿縐嶅拰鍓嶅摠鐗╃銆傞晧鏄搗宀稿甫鍜屾渤鍙ｇ幆澧冧腑鏅亶瀛樺湪鐨勬瘨鎬ц緝寮虹殑閲嶉噾灞炰箣涓�錛屽箍娉涘瓨鍦ㄤ簬娼棿甯︽矇縐墿涓�傛矇縐墿涓綔鍦ㄩ噴鏀劇殑闀夌瀛愭渶緇堥殢鍦拌〃寰勬祦榪涘叆娌挎搗姘村煙錛屼笉鍙伩鍏嶅湴鎹熷涓崕椴庛�備粠姣掔悊瀛﹁搴︽潵鐪嬶紝涓庝紶緇熸柟娉曠浉姣旓紝緇勫鍙互鏇寸洿鎺ャ�佸噯紜湴鍙嶆槧涓嶈壇鍚庢灉鐩稿叧鐨勫垎瀛愬姩鎬併�傛埅鑷崇洰鍓嶏紝閲嶉噾灞炴瘨鎬х爺絀朵富瑕侀泦涓簬椴庡嵉銆傚浜庢垚椴庯紝杈冨鐮旂┒嫻嬪畾鍏惰韓浣撳悇緇勭粐涓噸閲戝睘鍚噺銆傚皻鏃犲叧浜庢暣鍚堣漿褰曠粍瀛﹀拰浠ｈ阿緇勫璇勪及闀夊涓崕椴庡辜椴庢瘨鎬т綔鐢ㄧ殑鐩稿叧鐮旂┒鎶ラ亾銆?/p>
鍗楁搗鎵�椴庝繚鎶ゅ洟闃熺患鍚堟姉姘у寲鎸囨爣鍙婅漿褰曠粍瀛﹀拰浠ｈ阿緇勫鍒嗘瀽浜嗕腑鍗庨矌騫奸矌鐨勯晧瑙ｆ瘨鏈哄埗錛氾紙1錛夐嬈＄瓫閫夊嚭涓崕椴庡辜椴庨噸閲戝睘鑳佽揩涓嬬殑鏈�閫傚唴鍙傚熀鍥犱負Actin-related protein 5 (ARP5)銆傝綆梀n/n+1寰楀埌ARP5/SDHA銆丼DHA/18S rRNA鍜孉RP5/18S rRNA緇勫悎鍧囬�傜敤浜巕RT-PCR鍒嗘瀽涓崕椴庡辜椴庨噸閲戝睘鑳佽揩鍙嶅簲銆?nbsp;
浣跨敤geNorm杞歡璁＄畻娼滃湪鍐呭弬鍩哄洜騫沖潎琛ㄨ揪紼沖畾鍊糓 (A)鍜屾垚瀵瑰彉鍖栧�糣 (B)
娉細CD涓洪晧鑳佽揩錛汬G涓烘睘鑳佽揩
錛?錛夋姉姘у寲鎸囨爣SOD銆丆AT銆丮DA銆丮T鐨勬祴瀹氱粨鏋滄樉紺猴細闀夎儊榪細閫犳垚騫奸矌姘у寲搴旀縺鍙嶅簲錛屼笖闅忛晧嫻撳害鍗囬珮錛屽騫奸矌鍗卞涔熼殢涔嬪姞鍓с�?/p>
涓嶅悓嫻撳害闀夊SOD (a)鍜孋AT (b)鐨勬椿鎬с�丮DA鍚噺 (c)鍜孧T嫻撳害 (d)鐨勫獎鍝?/span>
錛?錛夎漿褰曠粍瀛﹀拰浠ｈ阿緇勫鍒嗘瀽鏄劇ず錛岄珮?gòu)箵搴﹂晧鑳仒q鑷翠腑鍗庨矌騫奸矌鐢樻補紓瘋剛浠ｈ阿绱婁貢浠ョ紦瑙ｉ晧鐨勬瘨鎬т綔鐢ㄣ�?/p>
緇煎悎杞綍緇勫拰浠ｈ阿緇勭殑鐩鎬簰緗戠粶錛堜嬌鐢∕etscape錛夈�傚熀鍥犱互鍦嗗湀琛ㄧず錛岃緭鍏ョ殑浠ｈ阿鐗╀互綰㈣壊鍏竟褰㈣〃紺恒�傜矇綰㈣壊鍏竟褰唬琛ㄤ竴鑸唬璋㈢墿錛屾綰㈣壊鍏竟褰唬琛ㄩ晧鑳佽揩涓嬪辜椴庡樊寮備唬璋㈢墿銆?/span>
錛?錛夊湪宸紓鍩哄洜涓紝緇嗚優(yōu)楠ㄦ灦鐩稿叧鍩哄洜 錛?em>tubulin銆乤ctin鍜?em>myosin heavy chain絳夛級鍦ㄩ晧鑳佽揩鍚庤榪囧害琛ㄨ揪錛岃�岃繖浜涘熀鍥犲浣曞弬涓庣粏鑳?yōu)楠ㄦ瀴檱嶅杩橀渶榪涗竴姝ョ爺絀躲�?/p>
鍏ㄦ枃閾炬帴錛?a >https://www.sciencedirect.com/science/article/pii/S0147651323000891
綺ゅ叕緗戝畨澶?4010502001742鍙?/a>